With respect to drug-enzyme interaction,

Question:

With respect to drug-enzyme interaction, identify the wrong statement:

  1. Non-Competitive inhibitor binds to the allosteric site

  2. Allosteric inhibitor changes the enzyme's active site

  3. Allosteric inhibitor competes with the enzyme's active site

  4. Competitive inhibitor binds to the enzyme's active site


Correct Option: , 3

Solution:

Some durg do not bind to the Enzyme's active site. These bind to a different site of enzyme which called allosteric site.

This binding of inhibitor at allosteric site changes the shape of the active site in such a way that substrate can not recognise it Such inhibitor is known as Non-competitive inhibitor.

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